VIAGRA was shown to potentiate the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors
4. Handling of missed doses or overdoses of Welgra 100
Select the format you want to export the citation of this publication. Multi-view semi-supervised adversarial attention network for drug repurposing, Computer Methods and Programs in Biomedicine, 282, (109406), (2026). Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation, Food Science & Nutrition, 14, 5, (2026). Artificial intelligence in drug research and development: a review of methods and applications in drug repurposing, Briefings in Bioinformatics, 27, 3, (2026). Endocrine-metabolic crosstalk in erectile dysfunction: mechanistic insights and therapeutic implications, International Journal of Impotence Research, (2026).
Can I take sildenafil every day?
Therapeutic applications of phosphodiesterase inhibitors in male reproductive health: narrative review, Sexual Medicine Reviews, 14, 2, (2026). Oral suspension versus tablet sildenafil for erectile dysfunction: a prospective multicenter comparative study on patient satisfaction, International Journal of Impotence Research, (2026). Low‐intensity shockwave therapy for erectile dysfunction: An abridged Cochrane review, BJU International, 137, 6, (949-957), (2026). Current state of the problem, Andrology and Genital Surgery, 25, 4, (33-40), (2026). Emerging Trends and Research Focus in Erectile Dysfunction Treatment: A 1993–2023 Bibliometric Analysis, Andrologia, 2026, 1, (2026).
Does Viagra increase a man’s sex drive?
The generic version of Viagra, sildenafil citrate, is expensive without insurance, costing over $1,400 for 30 tablets. Sildenafil is covered by health insurance for pulmonary hypertension but may not be for erectile dysfunction, depending on the insurer. Using a SingleCare prescription discount card can significantly reduce the cost of sildenafil, with prices potentially as low as $16 for 30 tablets. Sildenafil is the generic version of Viagra, the “little blue pill” used to treat erectile dysfunction (ED). However, sildenafil is also approved by the Food and Drug Administration (FDA) to treat pulmonary arterial hypertension (high blood pressure in the lungs’ arteries). such as organic nitrates or organic nitrites in any form is therefore contraindicated [see CONTRAINDICATIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY].
Parameter
Value
Description
Absorption Time
30-60 minutes
Time to reach peak plasma concentration
Bioavailability
40%
Percentage of dose that reaches systemic circulation
Half-life
4-5 hours
Time for plasma concentration to reduce by half
Metabolism
Liver (primarily CYP3A4)
Enzymes responsible for breakdown
Excretion
Feces and urine
Routes of elimination
When VIAGRA is co-administered with an alpha-blocker, patients should be stable on
Sildenafil’s effectiveness depends on sexual stimulation. It is not an aphrodisiac and requires arousal to work. Drinking large quantities of alcohol may impair its effectiveness. The drug can cause a prolonged erection if misused. Sildenafil may lead to sudden vision or hearing changes. Always discuss all medications you are taking with your doctor. Missing a dose should not be remedied by doubling the next dose. Use caution if you have a history of eye problems like retinitis pigmentosa. Consult your doctor before starting or stopping sildenafil treatment.
Sections or subsections omitted from the full prescribing information are not listed.
Sildenafil was originally developed to treat pulmonary hypertension. The 100 mg dosage is often prescribed when lower doses are ineffective. It can cause vision changes such as blurred vision or a blue tint. Alcohol consumption can enhance side effects and reduce effectiveness. Patients with heart conditions should consult a doctor before use. The medication is available by prescription only in many countries. Use with caution in patients with kidney or liver impairment. Report any allergic reactions like rash or difficulty breathing immediately. Sildenafil may cause dizziness; avoid operating heavy machinery after intake.
alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated
Product
Dosage
Quantity + Bonus
Price
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at 25 mg [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a
Condition
Details
Rationale
Temperature
Store below 25°C (77°F)
Preserves chemical stability
Humidity
Keep in a dry place
Prevents clumping and degradation
Light
Protect from direct sunlight
Prevents breakdown of active ingredient
Container
Original blister or tightly closed bottle
Maintains stability and prevents contamination
48 hour period because concomitant administration increased the blood levels of
About the Company
Humana drug lists for providers, Humana (2025) Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice. Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research. Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information. VIAGRA is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg, and 100 mg of sildenafil for oral administration. VIAGRA is indicated for the treatment of erectile dysfunction. sildenafil by 11-fold [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY].
Report Problems to the Food and Drug Administration
For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. The maximum recommended dosing frequency is once per day. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. VIAGRA may be taken with or without food. Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or saquinavir) or erythromycin.
6.1 Clinical Trials Experience
How much you pay for sildenafil depends on what you need it for, as different uses require different doses. People with pulmonary hypertension may have to take daily doses. In contrast, treating erectile dysfunction involves taking doses right before sexual activity, so prescriptions may be for only a few pills per month. Sildenafil is not only the generic version of Viagra, but it is also the active ingredient in Revatio, a brand-name drug that treats pulmonary arterial hypertension. Like Revatio, sildenafil can be administered as a tablet, oral suspension, or injection.
What does Viagra do for ED?
The cost of Viagra and Revatio will be different, and usually higher, than generic sildenafil. There are no over-the-counter versions of Viagra. People without insurance can expect to pay an average cash price of $1,424 for 30, 100 mg tablets of sildenafil, although prices vary by pharmacy and location. For erectile dysfunction, the prescription may be for fewer than 30 pills, so the price may be lower. With a SingleCare prescription discount card, you can get 30, 100 mg tablets of sildenafil for as low as $16.
Adjusting Your Sildenafil Dosage Over Time
The cost of sildenafil per pill depends on how many pills you pay for at once. If you purchase a 30-tablet supply of 100 mg tablets of sildenafil, you could pay $0.53 with a SingleCare coupon versus $47 per pill without SingleCare. People without insurance can expect to pay an average cash price of $1,064 for 10, sildenafil generic 100 mg tablets of brand-name Viagra, although prices vary by pharmacy and location. With a SingleCare prescription discount card, you can get 10, 100 mg tablets of brand-name Viagra for about $857. The cost of Viagra per pill depends on how many pills you pay for at once. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma
1. What is Kamagra 50mg or Kamagra 100mg?
If you purchase 10, 100 mg tablets of brand-name Viagra, you could pay about $85 per pill with a SingleCare coupon versus close to $106 per pill without SingleCare. As a treatment for pulmonary hypertension, sildenafil is usually covered by health insurance, Medicare drug plans, and Medicaid. Injections may not be covered or may require prior authorization before the insurance approves them. Copay costs are typically low, but other factors, such as coverage gaps, can influence the final out-of-pocket cost. As a treatment for erectile dysfunction, however, generic sildenafil may or may not be covered.
How to relieve Viagra side effects
Private or employer health insurance plans are more likely than Medicare or Medicaid to cover ED medication. The best advice for insured patients is to call the insurance company. If the insurance plan covers erectile dysfunction medications, generic sildenafil for ED treatment is probably covered, too. Keep in mind that while generic ED medications may be covered by insurance, brand-name versions may not be covered. If sildenafil prices are difficult to manage, ask your healthcare provider about sildenafil alternatives.
Key takeaways
For erectile dysfunction, there are other PDE5 inhibitors (phosphodiesterase-5 inhibitors) that work similarly to sildenafil and include Cialis (tadalafil) and Levitra (vardenafil). For people with pulmonary hypertension, sildenafil tablets, oral solutions, and injections are among the least expensive prescription medications used to control the condition. Tadalafil is an alternative PDE5 inhibitor used for pulmonary hypertension and may be less expensive than sildenafil. Other lower-cost treatments, like calcium channel blockers, diuretics, and digoxin, may be options for some patients, but other pulmonary hypertension drugs are usually more expensive. Keep in mind that pulmonary hypertension is a serious medical condition, and some medications may not be suitable for individual cases. levels of sildenafil by about 3 fold [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY].
Sildenafil 100 mg is part of a class of drugs called PDE5 inhibitors. It can be used in combination with other ED treatments if prescribed. Avoid using medications or supplements not approved by your doctor. The effect of sildenafil can be reduced by certain foods and medications. Be aware of your health conditions and discuss them with your doctor. Use the medication responsibly to minimize potential risks. Sildenafil should be used with caution in people with hepatic impairment. Check with your doctor if you experience persistent side effects. Never take medication that is not prescribed for you.
Consider a starting dose of 25 mg in patients > 65 years, patients with hepatic impairment (e.g., cirrhosis), and patients with severe renal impairment (creatinine
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RELATED: How to choose the best ED pill These are the most accurate medication prices as of Jan. 20, 2026, for the ZIP code 23666. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Sildenafil can be costly without insurance, but there are ways to reduce the price.
Does sildenafil interact with foods or drinks?
SingleCare’s lowest price for a 30-tablet supply of sildenafil is $16. Keep in mind that prices fluctuate and vary by pharmacy. To save, just show your prescription discount card at checkout. Alternatively, you can sildenafil 60mg compare prices on SingleCare.com or by using the SingleCare app. Simply inform your healthcare provider where to send your prescription, and then download the coupon for your preferred pharmacy to present at checkout.
Effectiveness and safety
Get your free SingleCare prescription discount card You may be able to save on Sildenafil by purchasing a 90-tablet supply instead of a 30-tablet supply. With a SingleCare coupon for Sildenafil, you could pay $0.53 per pill with a 30-tablet prescription or $0.33 per pill with a 90-tablet prescription. For pulmonary hypertension, it’s worth considering purchasing a health insurance policy. Pulmonary hypertension is a chronic and serious condition, so the expenses will add up. Costs do not only include medications, but also office visits, tests, and procedures. clearance <30 mL/minute) because administration of VIAGRA in these patients resulted in
Condition
Description
Additional Info
Erectile Dysfunction
Assists in achieving and maintaining erections
Most common use
Pulmonary Arterial Hypertension
Improves blood flow in lung arteries
Off-label use in some cases
Altitude Sickness
Potentially reduces symptoms
Not officially approved
Raynaud’s Phenomenon
Off-label to improve blood flow in extremities
Requires medical supervision
higher plasma levels of sildenafil [see Use In Specific Populations and CLINICAL PHARMACOLOGY].
How should this medicine be used?
Visit your state’s Health Insurance Marketplace to find the most affordable policies, or contact a local agent to help you find plans that cover sildenafil. Additionally, if there are other chronic health problems present, having health insurance coverage may be the best overall way to save money. The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Jan. 20, 2026. Visit our sildenafil coupon page for updated sildenafil prices near you.
